How acne treatments can alter skin microbiome

Jennifer E. Engen

It comes after scientists conducted a systematic review to assess the impact of acne treatment on the cutaneous microbial community, specifically of the bacterial flora, and examine the resultant changes in abundance and diversity of microbial strains.

While many acne treatments seek to target the bacteria Cutibacterium acnes​ (C. acnes​), they argued very little is known about how treatments affect the wider skin microbiome.

They also argued that very little is known about how individual differences in microbial composition affect disease severity.

In order to try and compile a clearer picture, they searched the available literature and assessed nine studies with 170 treated acne patients.

They used a method known as alpha diversity, which takes into account the total number of species in the sample and the proportion of the total sample taken up by each species, to judge abundance of various strains.

Five studies reported a significant change in alpha diversity following treatment, including three where antibiotics intake resulted in significant increases. The other two involved topical retinoids, despite the fact they are non-antimicrobial.

Furthermore, two of three studies examining effects of benzoyl peroxide reported a decrease in diversity.


With regard to increases in diversity, the researchers wrote: “The increase in microbial diversity following treatment could have been attributed to a decrease in relative abundance of C. acnes, allowing other microbial strains to proliferate.

Next Post

4 Best HGH Supplements for Men | Human Growth Pills For Sale in USA (2022)

Today’s article is a presentation and discussion of four (4) very dynamic and popular HGH (Human Growth Hormone) supplements. Do you know what HGH supplements are? One thing for sure is that these supplements are among the most trendy products in all gyms today. In this article, we explore some […]
4 Best HGH Supplements for Men | Human Growth Pills For Sale in USA (2022)